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Is Lactobacillus reuteri a prebiotic or probiotic?

4 min read

Over 50% of published research on Lactobacillus reuteri occurred within the last five years, highlighting its status as a widely studied bacterium. This raises a common question: Is Lactobacillus reuteri a prebiotic or probiotic? The answer lies in its nature as a live, beneficial microorganism.

Quick Summary

As a live microorganism, Lactobacillus reuteri is a probiotic that provides numerous health benefits when administered adequately. It helps to balance the gut microbiome, strengthen the intestinal barrier, and regulate immune function in the host.

Key Points

  • Probiotic, not Prebiotic: Lactobacillus reuteri is a living microorganism, categorizing it as a probiotic, not a prebiotic fiber.

  • Supports Gut Health: As a probiotic, L. reuteri colonizes the gut to balance the microbiome, combat pathogens, and strengthen the intestinal barrier.

  • Produces Antimicrobials: It produces compounds like reuterin, which gives it an edge in inhibiting the growth of harmful bacteria and fungi.

  • Relieves Digestive Issues: Research supports its use for relieving symptoms of infantile colic, diarrhea, and constipation.

  • Requires Prebiotics to Thrive: For maximum effectiveness, L. reuteri needs prebiotics (non-digestible fibers) as a food source to grow and proliferate in the gut.

  • Found in Supplements and Foods: L. reuteri is available in specific supplements and fortified foods like some yogurts and breast milk.

In This Article

The Fundamental Difference Between Prebiotics and Probiotics

Before determining the role of Lactobacillus reuteri, it is crucial to understand the distinct functions of prebiotics and probiotics. While both play vital roles in supporting a healthy gut, they are fundamentally different. Probiotics are the living organisms themselves, while prebiotics are the non-digestible food components that nourish them.

What Is a Probiotic?

According to the World Health Organization (WHO), probiotics are "live microorganisms which, when administered in adequate amounts, confer a health benefit on the host". These beneficial bacteria, or sometimes yeasts, are introduced into the body through fermented foods or supplements. Once in the digestive tract, they work to improve the balance of the gut flora, compete with harmful pathogens, and interact with the body's immune system.

What Is a Prebiotic?

Prebiotics are specialized, non-digestible fibers that act as food for the beneficial bacteria already present in the gut. These fibers pass through the upper gastrointestinal tract undigested and are fermented by the microbes in the colon. This fermentation process fuels the growth and activity of good bacteria, such as lactobacilli and bifidobacteria, and produces beneficial compounds like short-chain fatty acids (SCFAs), which are crucial for intestinal health. Common prebiotic sources include:

  • Onions and garlic
  • Asparagus
  • Bananas
  • Oats
  • Chicory root

Is Lactobacillus reuteri a Prebiotic or Probiotic?

Based on these definitions, the answer is clear: Lactobacillus reuteri is a probiotic. It is a living, beneficial bacterium found naturally in the gastrointestinal tract of humans and animals. When taken in supplements or certain fermented foods, it colonizes the gut and confers a variety of health benefits. Its classification as a probiotic is further supported by the production of antimicrobial compounds like reuterin, which helps it compete against other, more harmful microorganisms. It is also one of the most scientifically studied probiotics, with a strong safety record.

How Lactobacillus reuteri Benefits Health

Lactobacillus reuteri has been studied for its potential benefits across several health areas:

  • Digestive Health: It is known to reduce symptoms of infantile colic, decrease the duration of diarrhea in children, and may help manage constipation and symptoms of functional dyspepsia and IBS.
  • Immune System Support: Specific strains can modulate the immune system, helping to reduce pro-inflammatory cytokines and promote regulatory T-cell development. This can lead to a strengthened immune response and decreased inflammatory disease risk.
  • Oral Health: Research suggests L. reuteri can inhibit harmful oral bacteria, such as Streptococcus mutans, a key contributor to tooth decay.
  • Antimicrobial Action: It produces antimicrobial molecules, including reuterin, that help inhibit the growth of pathogenic bacteria, yeasts, and fungi.
  • Vaginal Health: Certain strains have been used to support women's intimate health and restore vaginal flora.
  • Nutrient Production: Some strains can produce essential vitamins, including B12 and folate.

Sources of Lactobacillus reuteri

Lactobacillus reuteri can be acquired through supplements and specific fermented foods:

  • Probiotic Supplements: Look for supplements that guarantee live and active cultures until the expiration date. Common strains include DSM 17938, ATCC PTA 6475, and RC-14.
  • Fermented Dairy: Some yogurts and kefirs are fortified with L. reuteri, though labels should be checked to ensure the specific strain is included.
  • Fermented Foods: Sourdough bread and certain fermented vegetables may contain lactobacilli, including reuteri.
  • Breast Milk: L. reuteri is found naturally in human breast milk and is a key contributor to the infant microbiome.

Prebiotics That Support L. reuteri

While L. reuteri is a probiotic, it relies on prebiotics to thrive. Providing the right type of fuel can significantly enhance its effectiveness within the gut microbiome. Certain dietary fibers act as excellent food sources for L. reuteri, helping it to colonize and proliferate. These include inulin-type fructans, found in chicory root, as well as galacto-oligosaccharides, which are present in legumes and milk. Combining prebiotic-rich foods with a L. reuteri supplement or food source can create a powerful symbiotic effect, a practice known as consuming a synbiotic.

Prebiotic vs. Probiotic: A Comparison Table

Feature Probiotics Prebiotics
Nature Live microorganisms (e.g., bacteria, yeast) Non-digestible dietary fibers
Function Populate and rebalance the gut microbiota directly Act as food to selectively feed beneficial bacteria already in the gut
Found in Fermented foods like yogurt, kefir, sauerkraut, kimchi, supplements High-fiber foods like garlic, onions, asparagus, bananas, oats
Interaction Must survive the acidic stomach environment to colonize the gut Fermented by gut bacteria in the large intestine
Synergy The seeds for a healthy gut flora The fertilizer that helps the seeds grow

Conclusion

In summary, Lactobacillus reuteri is definitively a probiotic, a live microorganism that confers health benefits when consumed. While it is not a prebiotic, it thrives on prebiotic fibers, which act as its food source. For optimal gut health, it is most effective to incorporate both a source of L. reuteri (such as a supplement or fortified food) and a diet rich in prebiotic fibers. This symbiotic approach ensures a robust and balanced microbiome, contributing to better digestion, enhanced immunity, and overall well-being. By understanding this crucial distinction, consumers can make informed choices to best support their digestive health.

Visit the NIH website for more detailed research on Lactobacillus reuteri

Frequently Asked Questions

The primary function of Lactobacillus reuteri is to act as a probiotic, colonizing the digestive tract to provide a range of health benefits, including balancing gut flora and strengthening the intestinal barrier.

Lactobacillus reuteri is available in probiotic supplements and certain fermented foods, such as specialized yogurts and some types of sourdough. It is also naturally present in human breast milk.

Prebiotics are non-digestible fibers that serve as food for beneficial gut bacteria, including Lactobacillus reuteri. Feeding these probiotics with prebiotics helps them thrive and enhances their beneficial effects.

It is generally recommended to take Lactobacillus reuteri at least 2 to 3 hours before or after an antibiotic dose, as antibiotics can kill the beneficial bacteria. Continuing supplementation after the antibiotic course can help restore gut flora.

Yes, several clinical studies have shown that supplementation with specific strains of Lactobacillus reuteri can significantly reduce crying time and fussiness in infants with colic.

Yes, the effects of probiotics are often strain-specific. For example, the strain DSM 17938 is well-documented for digestive health, while RC-14 is often studied for women's vaginal health.

A synbiotic is a combination of a probiotic (like Lactobacillus reuteri) and a prebiotic. This combination can enhance the survival and effectiveness of the beneficial bacteria in the gut.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.