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Is Splenda erythritol safe? A comprehensive review

5 min read

According to recent studies, erythritol, an ingredient in some Splenda products, has been linked to an increased risk of heart attacks and strokes in at-risk individuals. This has prompted many people to question: is Splenda erythritol safe? The answer is nuanced, depending on your health profile and the specific Splenda product you use.

Quick Summary

An examination of erythritol, a common ingredient in certain Splenda products, and its safety profile. Recent studies have highlighted potential cardiovascular risks, particularly for those with pre-existing conditions, while also noting its benefits for blood sugar and dental health.

Key Points

  • Cardiovascular Risk: Recent Cleveland Clinic studies linked high blood erythritol levels to an increased risk of heart attack and stroke, particularly in at-risk individuals.

  • Not All Splenda: Only certain Splenda products, primarily the "Natural" lines containing monk fruit or stevia, include erythritol. The classic yellow Splenda packets do not.

  • Absorption vs. Metabolism: Unlike other sugar alcohols, most erythritol is absorbed and excreted through urine, which typically prevents the digestive issues common with other polyols.

  • Regulatory Status: The FDA considers erythritol "Generally Recognized as Safe" (GRAS), meaning long-term safety studies were not required, leading to limited data on its long-term effects.

  • No Blood Sugar Impact: For individuals with diabetes, erythritol still has the benefit of not raising blood glucose or insulin levels.

  • Moderation is Key: Experts suggest that high intake, particularly for individuals with existing cardiac risks, warrants caution until more research is available.

In This Article

What is Erythritol?

Erythritol is a sugar alcohol (also known as a polyol) that is used as a zero-calorie sweetener. It is found naturally in some fruits like grapes and pears, and is also produced commercially through the fermentation of cornstarch. Unlike other sugar alcohols, it is mostly absorbed into the bloodstream and excreted unchanged in the urine, which means it is less likely to cause the digestive issues (like gas and bloating) associated with high consumption of other polyols.

For years, erythritol has been a popular sugar alternative, especially for those on ketogenic diets or managing diabetes, because it has a zero glycemic index and does not spike blood sugar or insulin levels. It is also known for not contributing to tooth decay.

The Heart Health Concerns with Erythritol

A pivotal study published in Nature Medicine in February 2023 significantly altered the public perception of erythritol's safety. Led by Dr. Stanley Hazen of the Cleveland Clinic, the research found a correlation between higher blood levels of erythritol and an increased risk of major cardiovascular events, such as heart attack, stroke, and blood clots.

Subsequent lab studies showed that erythritol could enhance platelet reactivity, making blood more prone to clotting. A key point from the research is that people with pre-existing heart disease risk factors, such as obesity and diabetes, were twice as likely to experience a cardiovascular event if they had the highest levels of erythritol in their blood. This does not mean erythritol causes heart disease, but that it may pose an additional risk factor for vulnerable individuals. The researchers emphasize that more long-term studies are needed to fully understand the implications.

Does Splenda contain Erythritol?

This is a critical distinction that is often misunderstood. Many consumers associate the name Splenda with the yellow packet containing sucralose and dextrose, which does not contain erythritol. However, other products under the Splenda brand, particularly the natural sweetener lines, do use erythritol as a primary ingredient.

For example, Splenda Naturals Stevia and Splenda Naturals Monk Fruit are blended with erythritol to add bulk and sweetness. Consumers must check the ingredient list on specific products, as the Splenda brand name alone is not a reliable indicator of whether erythritol is present.

Weighing the Benefits vs. Risks

Benefits of Erythritol

  • Zero Glycemic Index: Does not raise blood glucose or insulin levels, making it suitable for people with diabetes.
  • Zero Calories: Provides sweetness without contributing to calorie intake.
  • Dental Health: Helps prevent cavities by inhibiting the growth of oral bacteria.
  • Generally Well-Tolerated: Causes less gastrointestinal distress than many other sugar alcohols.

Risks and Concerns of Erythritol

  • Cardiovascular Risk: Recent studies suggest a link to increased blood clots, potentially raising the risk of heart attack and stroke, especially in at-risk individuals.
  • High Consumption: The quantities used in processed foods are often much higher than naturally occurring levels, potentially leading to higher blood concentrations.
  • Limited Long-Term Data: As the FDA classified it as "Generally Recognized as Safe" (GRAS), long-term safety studies were not required, leaving gaps in our understanding of its long-term effects.
  • Digestive Issues: Though less common than with other sugar alcohols, high intake can still cause stomach upset, bloating, and diarrhea in some individuals.

Splenda Original vs. Splenda Naturals: Ingredient Comparison

Feature Splenda Original (Yellow Packets) Splenda Naturals (Stevia/Monk Fruit)
Primary Sweetener Sucralose Stevia or Monk Fruit Extract
Bulking Agent Dextrose and Maltodextrin Erythritol
Caloric Value Trace amounts (not zero) Zero
Link to Erythritol Studies No Yes, contains erythritol
Potential Health Concerns Primarily focused on sucralose, not linked to recent erythritol findings Associated with recent studies linking high erythritol levels to cardiovascular risk

Conclusion

While traditional Splenda (sucralose) does not contain erythritol, many of the newer "natural" Splenda products do, a crucial detail for consumers concerned about recent health alerts. For the general healthy population, moderate consumption of products containing erythritol is unlikely to be a significant concern, but those with existing risk factors for cardiovascular disease, such as diabetes or high blood pressure, should exercise caution and consult their doctor. It is essential to read ingredient labels and to remember that minimizing all added sweeteners, both sugar and its substitutes, remains the healthiest approach overall. For individuals looking to reduce sugar intake, whole fruits or other less-processed options might be the safest long-term choice.

Additional Considerations and Resources

For those seeking more information, the World Health Organization (WHO) has provided guidelines suggesting caution with non-sugar sweeteners for weight control. Furthermore, a discussion with a healthcare provider can help you make a personalized decision based on your individual health profile. Minimizing added sugar and artificial sweeteners is a recommended strategy for overall wellness.

An excellent resource for understanding the complexities of sweeteners and recent research can be found in publications from the Cleveland Clinic, which has been at the forefront of the research into erythritol's potential cardiovascular risks.

What are some healthier alternatives?

If concerns about erythritol safety lead you to seek other options, consider these alternatives:

  • Whole Fruits: Naturally sweet and packed with fiber, vitamins, and minerals.
  • Stevia (Pure): Look for products that are pure stevia extract without added erythritol or other fillers.
  • Monk Fruit (Pure): Similar to pure stevia, choose products without any erythritol.
  • Minimal Sweeteners: The best approach for long-term health is often to reduce one's overall preference for sweet tastes.

Ultimately, deciding whether Splenda erythritol is safe for you depends on your personal health and risk factors. By staying informed and consulting with medical professionals, you can make the best choice for your well-being.

What's Next?

If you have concerns about erythritol consumption, consider speaking with a registered dietitian or your physician to determine the best course of action for your health needs.

Conclusion

Splenda's use of erythritol in some products raises valid questions about its safety, especially in light of recent studies linking it to increased cardiovascular risk in vulnerable populations. The key is to be a vigilant consumer, read labels carefully, and make choices that align with your health status. While erythritol remains a zero-calorie, zero-glycemic index option, a cautious approach is warranted for those with pre-existing heart conditions.

Final Recommendations

  • Read Labels: Always check the ingredients list to see if a product contains erythritol.
  • Limit High Doses: Be mindful of consuming large quantities of erythritol from multiple sources.
  • Consult Your Doctor: If you have heart disease or diabetes, discuss your sweetener use with a healthcare provider.
  • Focus on Whole Foods: Opt for naturally sweet whole foods like fruit rather than relying heavily on any sugar substitute.

Frequently Asked Questions

Erythritol is an ingredient in Splenda Naturals Monk Fruit and Splenda Naturals Stevia. The original yellow Splenda packets, liquid sweeteners, and granular sugar blends do not contain erythritol.

The recent cardiovascular risk concerns apply primarily to high consumption of erythritol, especially in at-risk individuals. While regular sugar has its own well-documented health problems, some experts now suggest erythritol may not be a harmless alternative, particularly for those with pre-existing heart conditions.

A study by the Cleveland Clinic showed that adding erythritol to blood samples increased the likelihood of platelet reactivity and heightened blood clot formation, although the full implications of this finding are still being studied.

While erythritol does not affect blood sugar or insulin levels, recent research suggests potential cardiovascular risks that could be particularly relevant for those with diabetes, who often have a higher baseline risk for heart issues. Diabetics should consult their doctor.

Compared to other sugar alcohols, erythritol is generally well-tolerated. However, in high doses, it can still cause digestive issues like bloating, cramping, and diarrhea in some sensitive individuals.

Splenda uses erythritol in its natural sweetener lines to add bulk and a taste that is more similar to sugar, as other natural sweeteners like stevia and monk fruit are much sweeter and can have a lingering aftertaste.

To avoid erythritol, always read the ingredient list on all packaged foods and sugar substitutes. Look for labels that explicitly state they are pure stevia or monk fruit without added erythritol.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.