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The Cacao Controversy: Does cacao cause inflammation in the body?

4 min read

A large-scale clinical trial known as the COSMOS trial found that daily cocoa flavanol supplements significantly reduced a key inflammatory biomarker in older adults. So, does cacao cause inflammation in the body? The answer is nuanced, depending heavily on the form and quality of the product consumed.

Quick Summary

Raw, unprocessed cacao is rich in anti-inflammatory compounds, but processing and added sugars can negate its benefits. The inflammatory potential depends on the product's quality, preparation, and sugar content.

Key Points

  • Cacao's Anti-inflammatory Compounds: Cacao contains powerful antioxidant polyphenols called flavanols that combat inflammation and oxidative stress.

  • Processing Matters: Minimally processed raw cacao retains the highest concentration of beneficial flavanols, while roasting and alkalization in standard cocoa can significantly reduce this content.

  • The Sugar Factor: The inflammatory potential of commercial chocolate is heavily influenced by added sugar. Excess sugar can trigger inflammation and negate cacao's health benefits.

  • Higher Cacao, Lower Risk: Choosing dark chocolate with 70% or more cacao is recommended, as it typically has a higher flavanol-to-sugar ratio, providing a more anti-inflammatory profile.

  • Gut Health Connection: Cacao's polyphenols may act as prebiotics, promoting healthy gut microbiota that can, in turn, help reduce inflammation.

In This Article

The Science Behind Cacao's Anti-inflammatory Power

Cacao beans are rich in plant-based compounds called polyphenols, primarily flavanols. These flavanols, including epicatechin and catechin, are potent antioxidants with significant anti-inflammatory effects. In the body, chronic inflammation is often linked to oxidative stress, a process where unstable molecules called free radicals cause cell damage. The antioxidants in cacao help neutralize these free radicals, thereby protecting cells and reducing inflammation.

The anti-inflammatory benefits are thought to be mediated by several mechanisms:

  • Inhibition of Inflammatory Signals: Cacao flavanols can suppress the activity of pro-inflammatory signaling pathways, such as nuclear factor kappa B (NF-κB), which regulates the expression of inflammatory proteins.
  • Improved Blood Flow: The flavanols in cacao enhance the production of nitric oxide, a molecule that relaxes and widens blood vessels. This improved circulation can reduce inflammation associated with cardiovascular disease.
  • Modulation of Gut Microbiota: Research indicates that unabsorbed cacao polyphenols in the colon act as prebiotics, promoting the growth of beneficial gut bacteria like Bifidobacterium and Lactobacillus. This microbial modulation helps trigger an anti-inflammatory response in the gut.

The Critical Role of Processing and Quality

Not all cacao products are created equal. The level of processing and the addition of other ingredients fundamentally alters the inflammatory potential of the final product. Understanding the difference between raw cacao and highly processed cocoa is crucial for maximizing health benefits.

Raw cacao is made from fermented, dried, and unroasted cacao beans. This minimal processing preserves the highest levels of beneficial flavanols and other nutrients. In contrast, standard cocoa powder is made from beans that have been roasted at high temperatures. This heat treatment significantly reduces the concentration of fragile flavanols. Furthermore, a process known as alkalization or Dutch-processing, which is used to reduce bitterness and darken the color of cocoa, can further strip away up to 60% of the remaining antioxidants.

The Impact of Added Sugar and Other Ingredients

While the cacao itself is anti-inflammatory, many commercially available chocolate products are loaded with added sugars and saturated fats. Sugar is a well-known trigger for inflammation in the body, which can negate the health benefits of cacao's flavanols. When choosing a product, it is vital to check the ingredient list for both the cacao percentage and the amount of added sugar.

For a truly anti-inflammatory treat, selecting a product with at least 70% cacao is recommended, as this typically signifies a higher flavanol content and lower sugar. The higher the percentage, the less sugar is generally included.

Comparison of Cacao Products

Feature High-Quality Raw Cacao Powder High-Sugar Milk Chocolate Bar
Processing Minimally processed (cold-pressed) Highly processed (roasted and often alkalized)
Flavanol Content High Low
Sugar Content None (unsweetened) High (often a primary ingredient)
Added Fats Minimal to none High (saturated fat)
Anti-inflammatory Potential High (due to high flavanol content) Low (sugar's pro-inflammatory effect can override cacao's benefits)
Caffeine/Theobromine Higher concentrations Lower concentrations

How to Integrate Cacao into Your Anti-inflammatory Diet

To reap the anti-inflammatory benefits of cacao without the drawbacks of sugar, follow these simple guidelines:

  • Choose the Right Type: Opt for raw, unsweetened cacao powder or dark chocolate with 70% cacao or higher. Check the label to ensure it is not Dutch-processed ('processed with alkali').
  • Portion Control: While beneficial, cacao products are calorie-dense. A small daily portion, like 1-2 tablespoons of cacao powder or a few squares of high-cacao dark chocolate, is sufficient.
  • Smart Pairings: Incorporate cacao into your diet by adding it to anti-inflammatory foods. Mix raw cacao powder into a smoothie with berries and leafy greens, sprinkle cacao nibs on oatmeal or yogurt, or add a spoonful to your coffee or hot tea.
  • Check for Heavy Metals: Some sources suggest potential heavy metal contamination in cacao, so choosing reputable, certified brands can be a wise precaution, especially for regular consumption.
  • Listen to Your Body: Cacao contains stimulants like caffeine and theobromine. Be mindful of your intake, particularly in the evening, if you are sensitive to their effects.

Conclusion

Ultimately, whether cacao causes inflammation depends on the form and quality of the product. High-quality, minimally processed cacao is rich in anti-inflammatory flavanols that can benefit health. However, in low-quality, high-sugar chocolate products, the pro-inflammatory effects of sugar and additives often outweigh the benefits of the cacao. By choosing dark chocolate with a high cacao percentage and using unsweetened cacao powder, you can incorporate this ingredient into a healthy, anti-inflammatory diet. It is essential to be a discerning consumer and prioritize products with high flavanol content and minimal processing to support your body's health.

This article is for informational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider before making significant changes to your diet, especially if you have a pre-existing medical condition.

Frequently Asked Questions

Yes, raw cacao powder is generally healthier because it is minimally processed and retains more of its natural anti-inflammatory compounds and antioxidants than standard cocoa powder, which is roasted at high temperatures.

Alkalized (Dutch-processed) cocoa has significantly lower levels of beneficial flavanols compared to natural or raw cacao. This processing method uses an alkali to reduce bitterness, but it destroys many of the potent antioxidant and anti-inflammatory properties.

The best way is to use unsweetened, non-alkalized raw cacao powder or high-cacao dark chocolate (70% or more). Add it to smoothies, oatmeal, or yogurt to avoid excess sugar.

Effective anti-inflammatory doses can vary, but studies often point to moderate daily consumption. A typical recommendation for dark chocolate is about 30-60 grams, or 1-2 tablespoons of high-flavanol cacao powder.

This depends entirely on the bar. A chocolate bar with a high cacao percentage (70%+) and low sugar can be beneficial. However, a milk chocolate bar with low cacao and high sugar will likely have a net pro-inflammatory effect.

Yes, excessive intake can lead to side effects related to its caffeine and theobromine content, such as nervousness, sleeplessness, or a fast heartbeat. High-cacao products are also calorie-dense and should be consumed in moderation.

Yes, studies suggest that cacao polyphenols can beneficially modulate the gut microbiota. By increasing beneficial bacteria, cacao can trigger an anti-inflammatory pathway in the gut and potentially improve intestinal health.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.