Chemical Structure and Metabolism
At a fundamental level, the difference between sugar and sugar alcohol lies in their chemical makeup. Standard sugars, like sucrose (table sugar), are carbohydrates that contain aldehyde or ketone groups. When consumed, they are rapidly digested and absorbed in the small intestine, breaking down into glucose and fructose, which are then used for immediate energy or stored. This quick absorption leads to a rapid rise in blood sugar levels and, consequently, a release of insulin.
Sugar alcohols, also known as polyols, are a type of carbohydrate derived from sugars. They undergo a process called hydrogenation, which replaces the aldehyde or ketone group with a hydroxyl (−OH) group, giving them a structure similar to both sugar and alcohol, but without the ethanol content. Because of this unique structure, the body does not fully absorb them during digestion. This incomplete absorption is the root cause of many of the key differences between the two.
Digestion and Physiological Response
The primary physiological difference is how the body processes these compounds. As mentioned, sugar is fully and quickly absorbed. Sugar alcohols, however, pass mostly through the small intestine and into the large intestine. Here, gut bacteria ferment the unabsorbed portion. This fermentation process is why excessive consumption can lead to gastrointestinal side effects like gas, bloating, and diarrhea. Some sugar alcohols, like erythritol, are absorbed but not metabolized, and are excreted largely unchanged in the urine, which is why they tend to cause fewer digestive issues.
Caloric Density and Blood Sugar Impact
Due to their incomplete absorption, sugar alcohols contribute fewer calories than sugar. While sugar provides roughly 4 calories per gram, most polyols offer about 1.5 to 3 calories per gram, with erythritol being nearly zero. The slow absorption of sugar alcohols also means they have a much lower glycemic index, causing a less dramatic impact on blood glucose and insulin levels. This makes them a popular alternative for individuals managing diabetes, though carbohydrate counting is still necessary.
Impact on Dental Health
One of the most significant advantages of sugar alcohols is their benefit to oral health. Unlike regular sugar, polyols cannot be fermented by the bacteria in your mouth that produce the acid responsible for tooth decay. In fact, some sugar alcohols, particularly xylitol, are actively used in dental products like toothpaste and chewing gum because they can help inhibit the growth of these cavity-causing bacteria.
Culinary Properties
Beyond the health aspects, there are notable differences in taste and application. Many sugar alcohols are less sweet than sucrose, requiring the use of larger quantities or a blend with other sweeteners to achieve the desired sweetness level. Some, like erythritol and xylitol, also have a unique endothermic reaction when dissolving, which creates a cooling sensation in the mouth. Furthermore, polyols do not caramelize or brown like sugar, which affects their use in certain cooking and baking applications.
Sugar vs. Sugar Alcohol: A Comparison Table
| Feature | Sugar (Sucrose) | Sugar Alcohol (Polyols) | 
|---|---|---|
| Chemical Structure | Contains aldehyde or ketone group. | Contains multiple hydroxyl (−OH) groups. | 
| Caloric Content | ~4 calories per gram. | 0–3 calories per gram (varies by type). | 
| Digestion | Rapidly and fully absorbed in the small intestine. | Partially and slowly absorbed; fermented by gut bacteria. | 
| Blood Sugar Impact | Causes a sharp increase in blood glucose and insulin. | Causes minimal rise in blood glucose and insulin. | 
| Dental Health | Promotes tooth decay via bacterial fermentation. | Non-cariogenic; some (xylitol) may prevent decay. | 
| Side Effects | Excess linked to obesity, diabetes, heart disease. | Potential for gastrointestinal distress (gas, bloating) with high intake. | 
| Relative Sweetness | Standard reference (100%). | Varies widely (e.g., lactitol 40%, xylitol 100%). | 
Conclusion
While sugar and sugar alcohol both serve as sweeteners, their differences extend far beyond taste. Sugar's complete absorption provides quick energy but at the cost of blood sugar spikes and dental health risks. In contrast, the incomplete absorption of sugar alcohols offers fewer calories and a more stable glycemic response, making them advantageous for managing diabetes and promoting oral health. However, the potential for digestive side effects and a slightly different taste profile means moderation is key for both. As new research emerges on potential risks, particularly with certain polyols like erythritol and xylitol, it's wise to consider all factors based on individual health needs. Prioritizing whole, naturally sweet foods remains the safest long-term approach for managing overall sugar intake. Harvard Health offers additional perspectives on navigating sugar substitutes effectively.