What is Sweetener 951?
Sweetener 951 is the European food additive code for aspartame, a non-nutritive, high-intensity artificial sweetener. A chemically synthesized substance, aspartame is approximately 200 times sweeter than regular table sugar (sucrose), meaning only a minute amount is needed to achieve the same level of sweetness. This potency is why it has become a staple in thousands of low-calorie and sugar-free products since it was first approved for use in the early 1980s.
The Chemical Composition of Aspartame
Aspartame is a dipeptide, which is a molecule composed of two amino acids: aspartic acid and phenylalanine. These two amino acids are naturally found in many protein-rich foods, including meat, eggs, and dairy. When ingested, the body metabolizes aspartame by breaking it down into these component amino acids, as well as a small amount of methanol. Because it is metabolized by the body, aspartame is technically a nutritive sweetener, though the calories per serving are negligible due to the small quantities used.
Where is Sweetener 951 Used?
Aspartame is widely used across the food and beverage industry to reduce sugar content and calories without sacrificing sweetness. However, it is not heat-stable, meaning it loses its sweetness when exposed to high temperatures. This characteristic limits its use primarily to products that do not require baking or extensive heat processing.
Common products containing sweetener 951 include:
- Diet or zero-sugar sodas and soft drinks
- Sugar-free chewing gums
- Low-calorie powdered drink mixes
- Flavored yogurts and low-fat dairy products
- Sugar-free gelatins, puddings, and desserts
- Tabletop sweeteners (often sold under brand names like Equal and NutraSweet)
- Certain breakfast cereals and granola bars
- Sugar-free cough drops and chewable vitamins
The Aspartame Safety Debate and Regulation
Sweetener 951 has been the subject of ongoing safety debates since its introduction. Concerns have ranged from headaches and mood changes to more serious claims involving cancer and neurological damage. However, extensive testing and scientific reviews by major regulatory bodies have repeatedly found aspartame to be safe for consumption within an Acceptable Daily Intake (ADI) level for the general population.
International Agency for Research on Cancer (IARC) vs. JECFA
A point of confusion for consumers arose in 2023 when the WHO's cancer research agency, IARC, classified aspartame as "possibly carcinogenic to humans" (Group 2B). This classification was based on limited evidence and indicates a potential cancer hazard, not the actual risk of getting cancer from normal consumption. Crucially, a separate joint expert committee of the WHO and Food and Agriculture Organization (JECFA), which assesses risk based on dietary intake, did not change its long-standing ADI. This reaffirms that moderate consumption within established daily limits does not pose a health concern.
The Exception: Phenylketonuria (PKU)
There is one specific health condition for which aspartame consumption is dangerous: Phenylketonuria (PKU). PKU is a rare genetic metabolic disorder in which the body cannot properly metabolize phenylalanine, one of the amino acids in aspartame. If not managed, high levels of phenylalanine can lead to serious health problems. For this reason, any product containing aspartame must include a warning label for individuals with PKU.
Aspartame vs. Other Artificial Sweeteners
Aspartame is just one of many artificial and natural sweeteners available. Each has a unique chemical structure, sweetness intensity, and application. Here is a comparison of aspartame to a few other common sweeteners:
| Feature | Aspartame (E951) | Sucralose (E955) | Stevia (E960) | 
|---|---|---|---|
| Sweetness | ~200 times sweeter than sugar | ~600 times sweeter than sugar | ~200–400 times sweeter than sugar | 
| Calories | Nutritive (4 cal/g), but negligible due to quantity used | Non-nutritive (zero calories) | Non-nutritive (zero calories) | 
| Heat Stability | Not heat-stable, loses sweetness when heated | Heat-stable, suitable for baking | Heat-stable, suitable for baking | 
| Composition | Two amino acids (aspartic acid and phenylalanine) | A modified sugar molecule with chlorine atoms | Plant-based extract from the stevia leaf | 
| Label Warning | Required for PKU patients (contains phenylalanine) | No specific warning required | No specific warning required for purified extract | 
Conclusion
Sweetener 951, or aspartame, is a potent artificial sweetener that offers a sugar-free, low-calorie option for a wide variety of foods and beverages. While its safety has been the subject of controversy over the decades, extensive evaluations by global health authorities like the FDA and EFSA have repeatedly concluded it is safe for consumption within established daily intake limits for most people. The main exception is for individuals with the rare genetic disorder PKU, who must avoid it due to its phenylalanine content. Like any food additive, moderate consumption and staying informed about reputable science are key to making informed dietary choices.
For those who wish to avoid aspartame, checking ingredient labels for 'sweetener 951' or 'aspartame' is the best course of action. With a growing number of natural and artificial sweetener options available, consumers have more choices than ever to satisfy their cravings while managing their sugar intake.
Disclaimer: The information in this article is for informational purposes only and does not constitute medical advice. Please consult with a healthcare professional for personalized guidance regarding dietary choices, especially if you have specific health concerns.