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What is the Italian fruit that lowers cholesterol? A look at bergamot's benefits

3 min read

Originating almost exclusively from the Calabria region of Southern Italy, the potent citrus fruit known as bergamot has been shown in multiple clinical trials to significantly reduce total and LDL cholesterol levels. Read on to understand the science behind what is the Italian fruit that lowers cholesterol and how it works to support cardiovascular health.

Quick Summary

Bergamot, a citrus fruit from Southern Italy, contains unique flavonoids that lower total and LDL cholesterol by inhibiting synthesis and absorption. It also boosts HDL cholesterol and supports overall heart health.

Key Points

  • Italian Origin: Bergamot (Citrus bergamia) is a citrus fruit native to Southern Italy, primarily grown in the Calabria region.

  • Cholesterol Reduction: Clinical studies have shown that bergamot extract can significantly reduce total cholesterol and LDL ('bad') cholesterol.

  • Multiple Mechanisms: Its polyphenols lower cholesterol by inhibiting its production in the liver and reducing its absorption in the intestine.

  • Potential for HDL: Some research also suggests that bergamot may help increase levels of HDL ('good') cholesterol.

  • Supplement Form: For reliable therapeutic effects, concentrated bergamot extract in capsule or powder form is recommended over relying on Earl Grey tea due to higher, standardized concentrations.

  • Consult a Doctor: Due to potential interactions with medications like statins, it is essential to seek medical advice before starting bergamot supplementation.

  • Mild Side Effects: Possible side effects include digestive upset and increased skin sensitivity to sunlight.

In This Article

What Is Bergamot?

Bergamot, scientifically known as Citrus bergamia, is a distinct citrus fruit primarily cultivated in the coastal region of Calabria, Southern Italy. While it resembles a cross between a lemon and a sour orange in appearance and taste, its intense sourness makes it unsuitable for eating raw. Historically, its extract and essential oil have been used in traditional Italian folk medicine, and its rind flavors Earl Grey tea. Its potent health properties, particularly for cholesterol, are a focus of modern research.

The Unique Mechanisms Behind Bergamot's Cholesterol-Lowering Effects

Bergamot manages cholesterol through a multifaceted approach involving flavonoids like brutieridin, melitidin, neoeriocitrin, and naringin. These compounds inhibit the enzyme HMG-CoA reductase, reducing cholesterol production, and reduce cholesterol uptake from the intestine. They also activate AMPK, important for lipid metabolism, and offer antioxidant support.

Research and Clinical Evidence

Multiple studies and a systematic review have confirmed bergamot's potential for improving lipid profiles. Research shows that oral bergamot extract can lead to significant reductions in total cholesterol, LDL-C ('bad' cholesterol), and triglycerides, with a modest increase in HDL-C ('good' cholesterol). Higher concentrations may produce greater reductions. Some studies suggest bergamot can be used with statins, potentially allowing for lower statin dosages. Healthline provides further details.

How to Incorporate Bergamot into Your Diet

For therapeutic benefits, supplements are often considered more effective than consuming large quantities of Earl Grey tea due to the typically low, non-standardized dose in tea. Bergamot is available in various forms, including pills, capsules, powder, liquid extract, or juice, with potency and concentration varying between forms.

Potential Side Effects and Interactions

Consult a healthcare provider before using bergamot, especially if on medication. Possible issues include mild digestive upset, heartburn, or muscle cramps, particularly with higher concentrations. Bergamot oil contains furanocoumarins that can increase sun sensitivity. Bergamot may interact with statins, diabetes medications, and blood pressure drugs. It is not recommended for pregnant or breastfeeding women and children due to limited safety data.

Comparison of Bergamot Consumption Methods

Here's a comparison to help you choose how to consume bergamot:

Method of Consumption Potency & Consistency Taste Precautions Ease of Use
Dietary Supplements Often offer standardized concentration, providing more reliable effects. Minimal taste. Potential drug interactions; consult a doctor. Very easy to incorporate.
Juice Variable concentration of polyphenols. Very sour and bitter. Photosensitivity risk may be higher. Can be less convenient than pills.
Earl Grey Tea Low and inconsistent flavonoid concentration. Distinctive citrus flavor. Minimal risks at typical levels. Very easy to find and prepare.

Conclusion

Bergamot, the Italian citrus fruit from Calabria, is a promising natural option for managing cholesterol. Its polyphenols and flavonoids help lower total and LDL cholesterol, increase HDL, and reduce triglycerides through distinct mechanisms. Bergamot should complement a heart-healthy lifestyle including diet and exercise. Consult a healthcare provider before adding bergamot supplements, especially if taking medication, to ensure safety and effectiveness.

Disclaimer: Information provided here is for general knowledge and informational purposes only, and does not constitute medical advice. Always consult with a qualified healthcare professional before making any decisions about your health or treatment.

Keypoints

  • Italian Origin: Bergamot (Citrus bergamia) is a citrus fruit native to Southern Italy, primarily grown in the Calabria region.
  • Cholesterol Reduction: Clinical studies have shown that bergamot extract can significantly reduce total cholesterol and LDL ('bad') cholesterol.
  • Multiple Mechanisms: Its polyphenols lower cholesterol by inhibiting its production in the liver and reducing its absorption in the intestine.
  • Potential for HDL: Some research also suggests that bergamot may help increase levels of HDL ('good') cholesterol.
  • Supplement Form: For reliable therapeutic effects, concentrated bergamot extract in capsule or powder form is recommended over relying on Earl Grey tea due to higher, standardized concentrations.
  • Consult a Doctor: Due to potential interactions with medications like statins, it is essential to seek medical advice before starting bergamot supplementation.
  • Mild Side Effects: Possible side effects include digestive upset and increased skin sensitivity to sunlight.

Frequently Asked Questions

Bergamot (Citrus bergamia) is a type of citrus fruit, thought to be a hybrid between a lemon and a sour orange. Its appearance and taste are similar to a bitter lemon.

No, Earl Grey tea contains bergamot extract for flavor, but the concentration of active flavonoids is typically too low to produce the therapeutic effects seen in studies. Supplements often provide a standardized, concentrated amount.

While some bergamot compounds can inhibit a similar enzyme to statins, bergamot also works through distinct mechanisms like reducing cholesterol absorption in the gut and activating AMPK, offering a unique multi-pronged approach.

Yes, some people may experience mild side effects, including digestive upset, heartburn, and muscle cramps. Additionally, bergamot can increase skin sensitivity to sunlight.

Pregnant and breastfeeding women, children, and individuals with a history of photosensitivity or who are taking medications for diabetes, high blood pressure, or cholesterol should avoid or use bergamot with caution.

Clinical studies have shown that it can take several weeks to see a significant improvement in cholesterol levels, with some trials lasting up to six months.

Determining the right amount of bergamot extract for individual needs should be done in consultation with a healthcare professional, as they can provide personalized guidance.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.