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What Supplements Does Dr. Hyman Recommend for Foundational Health?

4 min read

According to Dr. Mark Hyman, a leading functional medicine expert, modern agricultural methods and nutrient-depleted soil have made it difficult to get all essential nutrients from food alone, which is why he recommends a strategic approach to supplementation. His protocol focuses on core foundational supplements to fill nutritional gaps for most people, alongside targeted recommendations for specific health concerns.

Quick Summary

Dr. Hyman outlines key foundational supplements, such as a high-quality multivitamin, vitamin D3, omega-3s, and magnesium, to build a base for overall wellness. His approach emphasizes filling nutrient gaps left by modern diets and addresses specific health goals with tailored supplement stacks.

Key Points

  • Foundational Five: Dr. Hyman recommends a multivitamin, Vitamin D3, omega-3s, magnesium, and a probiotic as a baseline for optimal health.

  • Quality Over Quantity: He emphasizes choosing high-quality, hypoallergenic supplements from trusted brands like Pure Encapsulations and Thorne to avoid toxins and allergens.

  • Targeted Protocols: For specific issues like brain health, he suggests additional supplements like CoQ10, NAC, and magnesium L-threonate.

  • Personalized Approach: A functional medicine perspective means tailoring supplement protocols to individual needs and deficiencies, not a one-size-fits-all solution.

  • Food First: Supplements are intended to complement, not replace, a healthy diet rich in whole foods, vegetables, and healthy fats.

  • Consider the Form: With supplements like magnesium, the specific form (e.g., glycinate vs. citrate) matters for the intended effect.

In This Article

Dr. Hyman’s Foundational Supplement Stack

Dr. Hyman's approach to supplementation is rooted in functional medicine, which focuses on addressing the root causes of illness rather than just treating symptoms. He views supplements not as replacements for a healthy diet but as a crucial "insurance policy" to compensate for the decline in modern food's nutrient density. He often outlines a "Foundational Nutritional Support Stack" that he considers essential for almost everyone.

The core components of Dr. Hyman’s foundational stack typically include:

  • High-Quality Multivitamin: This serves as the nutritional safety net, providing a comprehensive spectrum of essential vitamins and minerals. He often suggests multivitamins from brands he trusts, such as Pure Encapsulations, Metagenics, or Designs for Health, and notes that a sufficient amount may require several capsules daily.
  • Vitamin D3: Calling vitamin D deficiency an "epidemic," Dr. Hyman emphasizes its critical role in immune function, metabolism, and regulating over 200 genes. He typically recommends an intake level of Vitamin D based on blood levels, and specifies the more biologically active D3 (cholecalciferol) form.
  • Omega-3 Fatty Acids (EPA and DHA): Foundational for heart and brain health, omega-3s help reduce inflammation, improve insulin sensitivity, and support neurological function. He recommends Omega-3s daily, often from purified fish oil.
  • Magnesium: Involved in over 600 enzymatic reactions in the body, magnesium is crucial for everything from muscle function and sleep to blood sugar control. Dr. Hyman recommends different forms for different needs: magnesium glycinate for daily support, and magnesium citrate for those experiencing constipation.
  • Probiotics/Synbiotics: For a healthy gut microbiome, Dr. Hyman suggests a combination of probiotics and prebiotics. This supports digestion, nutrient absorption, and helps maintain a healthy gut lining. A specific product he has endorsed is the DS-01 Daily Synbiotic by Seed.

Targeted Supplement Recommendations

Beyond the foundational stack, Dr. Hyman suggests additional supplements for specific health goals or conditions, based on a functional medicine assessment.

For Brain Health & Cognition:

  • Coenzyme Q10 (CoQ10): A potent antioxidant important for cellular energy production, CoQ10 levels decline with age. It is recommended for cardiovascular support and mitochondrial health.
  • N-acetyl Cysteine (NAC): As a precursor to glutathione, the body's master antioxidant, NAC supports detoxification and immune function.
  • Adaptogens: Herbs like Ashwagandha can be recommended to help the body manage stress.
  • Memory Support Stack: For enhanced cognitive function, he has a specialized stack including NeuroMag (Magnesium L-threonate) and Memory Pro, which contains ingredients like Bacopa and Phosphatidylserine.

For Healthy Aging:

  • Nicotinamide Mononucleotide (NMN): This compound is used to support NAD+ levels, which are linked to healthy cellular aging.
  • Himalayan Tartary Buckwheat (HTB): Rich in antioxidants, this supplement supports overall wellness and immune function.
  • Senolytic Synergy: A blend of Quercetin and Fisetin, taken intermittently to support healthy aging and cell function.

For Gut Health & Digestion:

  • PGX (PolyGlycopleX): A fiber supplement to slow sugar absorption and help with satiety and weight management.
  • Digestive Enzymes: To assist with breaking down food and improving nutrient absorption.
  • L-Glutamine: An amino acid that helps repair the gut lining and support its integrity.

Understanding Different Magnesium Forms

Dr. Hyman advocates for specific forms of magnesium depending on the desired health outcome. Not all magnesium supplements are created equal, and their bioavailability and effects differ.

Magnesium Form Primary Use Notable Effects Recommended Brands (as per Dr. Hyman)
Magnesium Glycinate General daily supplementation, anxiety, sleep Highly bioavailable, calming effect, less laxative than other forms Designs for Health
Magnesium Citrate Constipation relief, bowel regularity Has a laxative effect, helps stimulate bowel movements Pure Encapsulations
Magnesium L-Threonate Brain health, memory, cognitive function Can cross the blood-brain barrier, may improve cognitive abilities NeuroMag (specific product)

Choosing Quality Supplements

Beyond which supplements to take, Dr. Hyman stresses the importance of choosing high-quality products. He advises looking for brands that ensure purity and are free from common allergens like gluten, dairy, or soy. He mentions brands like Designs for Health, Pure Encapsulations, and Thorne as reliable choices. He recommends checking labels carefully and consulting reputable sources like PubMed for research on specific nutrients.

Conclusion: A Personalized, Food-First Approach

While Dr. Hyman recommends a core set of foundational supplements, his overall philosophy emphasizes a personalized, functional medicine approach. He advocates for a nutrient-dense, whole-foods diet as the primary basis for health, with supplements serving as an important tool to fill gaps and target specific needs. It is crucial to remember that this is a general guideline and individual needs can vary greatly. Always consult with a healthcare provider trained in functional medicine before starting any new supplement regimen to ensure it is appropriate for your unique health profile and goals. For more detailed information on his approach, his website is a comprehensive resource: Mark Hyman, MD.

Frequently Asked Questions

Dr. Hyman views a high-quality multivitamin as a nutritional safety net, providing a baseline of essential vitamins and minerals that can be difficult to obtain solely from modern food sources.

Dr. Hyman recommends Vitamin D3 because it is critical for immune function, hormone balance, and metabolism, and he notes that deficiency is widespread.

He suggests purified fish oil containing EPA and DHA, emphasizing its benefits for reducing inflammation, supporting heart and brain health, and improving insulin sensitivity.

He recommends magnesium glycinate for general support, sleep, and anxiety, while suggesting magnesium citrate for those needing a laxative effect for constipation relief.

For gut health, Dr. Hyman includes a prebiotic/probiotic combo like Seed's DS-01 Daily Synbiotic in his foundational stack and also mentions other products like L-glutamine and digestive enzymes.

Yes, for brain health and cognitive function, Dr. Hyman recommends targeted supplements like CoQ10, NAC, and Magnesium L-Threonate, which is found in products like NeuroMag.

No, Dr. Hyman explicitly states that supplements are not a replacement for healthy eating. They are meant to complement a nutrient-dense, whole-foods diet and serve as an "insurance policy" against nutritional gaps.

Dr. Hyman often mentions and utilizes brands such as Designs for Health, Pure Encapsulations, Thorne, and Metagenics in his protocols.

CoQ10 is an antioxidant recommended for supporting cellular energy production and cardiovascular health, which is particularly relevant as its levels decrease with age.

Yes, for healthy aging, he has mentioned compounds like Nicotinamide Mononucleotide (NMN), Himalayan Tartary Buckwheat (HTB), and a blend of Quercetin and Fisetin called Senolytic Synergy.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.