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Nutrition Diet: What are the diseases caused by processed foods?

6 min read

According to a 2024 umbrella review published in The BMJ, higher consumption of ultra-processed foods was consistently associated with a greater risk of over 30 adverse health outcomes, ranging from cardiovascular problems to mental disorders. This compelling evidence highlights the serious long-term consequences of the diseases caused by processed foods, affecting multiple interconnected systems within the body.

Quick Summary

Regular consumption of ultra-processed foods increases the risks of cardiovascular disease, type 2 diabetes, obesity, certain cancers, and mental health issues. These health problems arise from poor nutritional quality, inflammatory additives, and the displacement of whole foods from the diet.

Key Points

  • Cardiovascular Disease: Diets high in ultra-processed foods are linked to an increased risk of heart disease, stroke, and hypertension due to excess sodium, unhealthy fats, and chronic inflammation.

  • Type 2 Diabetes: Ultra-processed food consumption is strongly associated with a higher risk of developing type 2 diabetes, primarily driven by high sugar, refined carbohydrates, and weight gain.

  • Cancer Risk: Studies show an increased risk for specific cancers like colorectal, breast, and ovarian cancer, potentially linked to obesity, certain food additives, and inflammatory effects of UPFs.

  • Mental Health: High intake of ultra-processed foods is correlated with higher rates of depression, anxiety, and cognitive decline, influenced by gut-brain axis disruption and inflammation.

  • Gut Health: UPFs can cause intestinal dysbiosis and increase gut permeability, leading to a state of chronic systemic inflammation that underlies numerous chronic diseases.

  • Additives and Ingredients: Harmful additives, trans fats, and high levels of salt and sugar are key culprits, often displacing nutrient-dense whole foods from the diet.

In This Article

The modern food landscape is dominated by convenience, and at the heart of this convenience lies a vast category of products known as processed foods. While simple processing methods like pasteurization or canning can make food safer and more accessible, the deepest health concerns are centered on ultra-processed foods (UPFs). The NOVA classification system defines UPFs as industrial formulations made with five or more ingredients, often including additives, colors, and preservatives not used in home cooking. These are the foods most strongly linked to a range of chronic health conditions. This guide explores the scientific consensus on how these products can negatively affect health, from disrupting metabolic function to fueling chronic inflammation.

Major Health Consequences Linked to Processed Foods

Cardiovascular Disease

Consuming a diet high in ultra-processed foods significantly increases the risk of cardiovascular disease (CVD), including heart attack, stroke, and hypertension. Factors such as high levels of sodium, unhealthy fats, and additives contribute to increased blood pressure, harmful cholesterol levels, obesity, and chronic inflammation, all of which are detrimental to heart health.

Type 2 Diabetes and Metabolic Syndrome

There is a strong link between high ultra-processed food intake and an elevated risk of developing type 2 diabetes. A meta-analysis indicated that for every 10% increase in UPF consumption, there was a 15% higher risk of type 2 diabetes. This is attributed to the high glycemic load of these foods causing blood sugar spikes, promotion of weight gain leading to insulin resistance, and the potential impact of additives on glucose metabolism.

Cancer Risk

Studies suggest an association between diets high in ultra-processed foods and an increased risk of certain cancers, including colorectal, breast, and ovarian cancer. This connection is believed to be influenced by the link between UPFs and obesity, the presence of potentially carcinogenic additives like nitrates, and the role of inflammation in tumor development. Additionally, chemicals from food packaging may play a role.

Mental Health and Neurological Issues

Research points to a link between high ultra-processed food consumption and mental health disorders such as depression and anxiety, as well as accelerated cognitive decline. This is thought to be mediated by the gut-brain axis, where UPFs can negatively impact the gut microbiome, affecting mood-regulating neurotransmitters and contributing to mood instability through blood sugar fluctuations.

Gut Health and Chronic Inflammation

Ultra-processed foods can harm gut health by lacking fiber essential for beneficial bacteria, leading to an imbalance known as dysbiosis. Additives can also alter gut bacteria and damage the intestinal barrier, potentially causing a "leaky gut". This can allow harmful substances into the bloodstream, triggering chronic systemic inflammation, which is linked to numerous major diseases.

Ultra-Processed vs. Minimally Processed: A Comparison

To understand the health risks, it is helpful to distinguish between different levels of food processing. The table below outlines the key differences between ultra-processed and minimally processed foods, based on the NOVA classification system.

Feature Ultra-Processed Foods (UPFs) Minimally Processed Foods
Definition Industrially formulated products with five or more ingredients, often including industrial additives and substances. Natural foods altered only by standard techniques like washing, drying, or pasteurization without adding chemicals.
Ingredients Long lists of ingredients, including artificial flavors, colors, emulsifiers, sweeteners, and preservatives. Few ingredients, recognizable as whole foods (e.g., nuts, pasteurized milk, frozen vegetables).
Nutritional Value Generally poor; high in calories, sodium, unhealthy fats, and added sugars, but low in fiber, vitamins, and minerals. High in essential nutrients, fiber, vitamins, and minerals. Retains most of its nutritional integrity.
Energy Density High energy density, often designed to be hyper-palatable and promote overconsumption. Lower energy density, containing more fiber and water, which promotes satiety.
Health Effects Linked to increased risk of obesity, T2D, CVD, cancer, and mental health issues. Associated with better overall health outcomes and reduced risk of chronic diseases.

How to Reduce Your Intake

Reducing the consumption of ultra-processed foods is a significant step for improving long-term health. The aim is to prioritize whole and minimally processed options. This can be achieved by reading food labels for long lists of unfamiliar ingredients, cooking more meals at home, making simple swaps like choosing fresh fruit over packaged snacks, increasing the intake of whole foods, and opting for water instead of sugary drinks.

Conclusion

Understanding the diseases caused by processed foods, particularly ultra-processed varieties, is crucial for protecting long-term health. The substantial evidence connecting UPFs to various chronic illnesses underscores the importance of dietary choices. By distinguishing between minimally and ultra-processed foods and making gradual, sustainable changes to prioritize nutrient-dense options, individuals can significantly lower their health risks and improve overall well-being. Additional resources on ultra-processed foods and heart health are available from organizations like the American College of Cardiology.

Actionable Steps for a Healthier Diet

  • Prioritize whole foods: Build your meals around unprocessed or minimally processed options like fresh fruits, vegetables, legumes, and whole grains.
  • Limit ultra-processed convenience: Intentionally reduce intake of packaged snacks, sugary cereals, and ready-made meals that are high in additives and unhealthy ingredients.
  • Become a label detective: Scrutinize ingredient lists for additives, preservatives, and long lists of unfamiliar names, which are hallmarks of ultra-processing.
  • Cook more, outsource less: Prepare meals from scratch more often to control the quality of your ingredients and avoid harmful additives.
  • Understand the 'why': Remember that the issue with UPFs isn't just about weight gain, but also the systemic inflammation and gut damage they cause over time.

Ultra-processed vs. Minimally processed: A comparison

Feature Ultra-Processed Foods (UPFs) Minimally Processed Foods
Definition Industrially formulated products with five or more ingredients, often including industrial additives and substances. Natural foods altered only by standard techniques like washing, drying, or pasteurization without adding chemicals.
Ingredients Long lists of ingredients, including artificial flavors, colors, emulsifiers, sweeteners, and preservatives. Few ingredients, recognizable as whole foods (e.g., nuts, pasteurized milk, frozen vegetables).
Nutritional Value Generally poor; high in calories, sodium, unhealthy fats, and added sugars, but low in fiber, vitamins, and minerals. High in essential nutrients, fiber, vitamins, and minerals. Retains most of its nutritional integrity.
Energy Density High energy density, often designed to be hyper-palatable and promote overconsumption. Lower energy density, containing more fiber and water, which promotes satiety.
Health Effects Linked to increased risk of obesity, T2D, CVD, cancer, and mental health issues. Associated with better overall health outcomes and reduced risk of chronic diseases.

How to Reduce Your Intake

Minimizing the intake of ultra-processed foods is one of the most impactful dietary changes you can make for your long-term health. The goal isn't necessarily to eliminate all processed foods but to prioritize whole and minimally processed options.

  • Read Food Labels: A long ingredient list featuring items you wouldn't find in your kitchen is a strong indicator of a UPF. Opt for products with shorter, recognizable ingredient lists.
  • Cook from Scratch: Cooking meals at home gives you full control over the ingredients. Simple, whole-food-based meals like stir-fries or soups are quick to prepare and highly nutritious.
  • Make Simple Swaps: Replace packaged snacks with fresh fruit, nuts, or homemade popcorn. Choose plain yogurt and add your own fruit instead of flavored varieties. For example, instead of processed meat like sausages, choose leaner, minimally processed options like chicken breast.
  • Increase Whole Foods: Intentionally increase your consumption of whole grains, fruits, vegetables, legumes, and lean proteins to naturally displace UPFs in your diet.
  • Drink More Water: Swap out sugary drinks and juices for water, which helps reduce your intake of liquid sugar and artificial additives.

Conclusion

Understanding what are the diseases caused by processed foods, particularly ultra-processed ones, is a critical step toward protecting long-term health. The extensive evidence linking UPF consumption to a broad spectrum of chronic illnesses—from heart disease and cancer to mental health and inflammation—is compelling. By recognizing the differences between minimally processed and ultra-processed options, and by implementing small, sustainable dietary changes, individuals can significantly mitigate these risks. Prioritizing whole, nutrient-dense foods is the most effective strategy for nurturing the body and promoting overall well-being. For more detailed nutritional guidance, consider visiting the American College of Cardiology's resources on ultra-processed foods and heart health.

Frequently Asked Questions

Processed foods are simply altered from their natural state, like canned beans or frozen vegetables. Ultra-processed foods, by contrast, are industrial formulations made with numerous ingredients, including many additives, and bear little resemblance to whole foods.

No, not all processed foods are bad. Minimally processed foods like pasteurized milk, whole-grain bread, and frozen vegetables can be part of a healthy diet. The primary health risks are associated with ultra-processed foods.

UPFs contribute to heart disease through several pathways, including high sodium content that raises blood pressure, unhealthy fats that increase cholesterol, and additives that trigger chronic inflammation and metabolic issues.

These foods often have a high glycemic load, causing blood sugar spikes and insulin resistance. Their high calorie density also contributes to weight gain, a major risk factor for type 2 diabetes.

Yes, research indicates that a high intake of ultra-processed foods is linked to an increased risk of depression and anxiety. This may be due to gut microbiome disruption, inflammation, and blood sugar fluctuations.

Many ultra-processed foods and their additives trigger chronic, low-grade systemic inflammation by disrupting the gut microbiome and damaging the intestinal lining, or gut barrier.

To reduce your intake, you can swap sugary snacks for fresh fruit or nuts, choose plain yogurt over flavored versions, and cook more meals from scratch rather than relying on ready-made options.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.